Roadmap to a Cure
Estimated Time Lines and Costs
Mouse Models
- Need 3-4 mouse models with reproducibility
- 1-1.5 yr/ mouse
- $100,000/ mouse
- Characterization: $50,000/mouse
iPS Cells
- Need 3-4 cell lines with reproducibility
- Correlation to Mouse lines helpful
- $100,000 to $300,000
- 6-8 months per line
Protein Target Identification
- Proteomics $50,000
- Mass spectrometry $30,000
- 1-2 years
Drug Discovery, Screening and Development
Phase I (Drug) Clinical Trial
Phase II (Pilot) Clinical Trial
Phase III Clinical Trial
DATA BASE
- Ongoing
- Critical for determining Therapeutic Endpoints for Trials
- $75,000
Roadmap to a Cure