CURRENT RESEARCH FOR CDKL5 Funded by IFCR
Your research dollars at work!
Mouse Model (Knock-In)
IFCR has just begun a second mouse model with Dr. Zhaolan (Joe) Zhou at the University of Pennsylvania. Read more
Development of iPS cells and Differentiation into Neurons
Create induded pluripotent stem cells from skin fibroblasts of patients with CDKL5 and differentiate into neuronal cells. Read more
Mouse Model (Knock out)
Create CDKL5 Knockout mouse model (Generate a mouse that lacks the Cdkl5 gene).
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CDKL5 Antibody Development
Create 2 different antibodies against the CDKL5 protein to be used for future studies utilizing Immunflourescence for Enzyme Linked ImmunoSorbent Assays (ELISA)
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Determination of CDKL5 Function
Variety of approaches using mice, iPS, and cell cultures to determine CDKL5 function
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Additional CDKL5 Projects
iPS Cell Lines
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Determination of CDKL5 Function
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