Tools for Investigators
Animal & Cell Models
Mutant Mouse Resource & Research Center (MMRRC) Mouse Models
Floxed allele, exon 4 was targeted to create a conditional knockout allele and can be found here.
R175S missense mutation results in production of full length CDKL5 protein with a point mutation and can be found here.
This nonsense mouse model bears a c.2564C>G exchange, predicting premature truncation at p.Ser855 mutation in Cdkl5 and can be found here.
Jax Mouse Models
The latest update and report on the Phenotyping of CDKL5 Mice.
Zebrafish & iPSC lines
ENU Zebrafish can be found here.
iPSC cell lines can be found here.